What disease is levamisole hydrochloride used for

Levamisole hydrochloride as a modulator of immunity and deworming can improve some symptoms. There are levamisole hydrochloride tablets and levamisole hydrochloride injections, one for oral administration and one for injection.

Levamisole hydrochloride tablets is a broad-spectrum anthelmintic drug, mainly used to repel roundworms and hookworms. This product can improve the patient's resistance to bacterial and viral infections.

What disease is levamisole hydrochloride used for

It is currently used as an adjuvant treatment for lung cancer, breast cancer after surgery or acute leukemia and worsening lymphoma after chemotherapy. In addition, it can still be used for autoimmune diseases such as rheumatoid arthritis, lupus erythematosus and upper flu, respiratory tract infections in children, hepatitis, bacillary dysentery, boils, abscesses, etc. Preliminary use of refractory bronchial asthma has been proved to be effective in the short term.

Levamisole hydrochloride tablets have a good effect on roundworms, hookworms, pinworms and strongyloidiasis. Because the single-dose of the product has a higher effect rate, it is suitable for group therapy. It is more active against bancrofti, malayi, and onchocerciae adults and microfilaria than ethamazine, but the long-term curative effect is poor.

Pharmacology and Toxicology of Levamisole Hydrochloride Tablets

Levamisole hydrochloride tablets are the levorotatory form of tetraimidazole, which can selectively inhibit the succinate dehydrogenase in the worm body muscles, so that fumaric acid cannot be reduced to succinic acid, thereby affecting the anaerobic metabolism of the worm body muscles and reducing energy production. When the worm body comes into contact with it, it can depolarize the nerve and muscle, and the muscle will continue to contract and cause paralysis; the cholinergic effect of the drug is conducive to the discharge of the worm body. Its activity is about 1 to 2 times that of tetraimidazole (racemate), but its side effects are lower. In addition, the drug may have an inhibitory effect on the microtubule structure of the worm. Levamisole also has immune regulation and immune excitability functions.

Medicine interactions

Combination with pyrantel can treat severe hookworm infections and improve the effect of repelling American hookworms.

Combination with thiabendazole can treat mixed infections of intestinal nematodes.
Sequential application with ethamazine citrate can treat filarial infections.
It should not be combined with tetrachloroethylene, so as not to increase its toxicity.

Can Levamisole Hydrochloride Injection Repel Tapeworms in Dogs?

As a Levamisole Hydrochloride Injection factory, it is generally used to take in vivo deworming tablets. According to the exact deworming time, dogs are dewormed once at 4, 8 and 12 weeks of age. After 12 weeks of age, regular deworming every 3 months thereafter will do.

Note

Deworming and vaccination can only be done when the dog is healthy. Some dogs will have a stress reaction after deworming, which is easy to cause gastrointestinal problems. You can feed the dog a few days of gastrointestinal treasure during deworming, which can enhance the dog’s immunity and avoid stress reaction.