Form a protective barrier on the surface of mucous membrane, interact with capsulovirus, reduce the infection ability of capsulovirus, prevent capsulovirus infection, and has good inhibitory effect on pseudorabies virus (PRV), porcine parvovirus (PPV), transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV) and African swine fever virus (ASFV).
Effect of anti plague companion on anti-virus cells infected with African classical swine fever virus in porcine alveolar macrophages
Positive control group Anti plague compaonin group
The mucosal immune system mainly includes the mucosa of digestive tract, respiratory tract, urogenital tract and the lymphoid tissue of some exocrine glands. M cells, which are unique in the mucosal immune system and located between the mucosal epithelium, can effectively absorb the antigen in the mucosal cavity, and present the antigen to the dendritic cells, macrophages, t, B lymphocytes and other immune cells in the lower part (PP node), so as to induce antigen-specific immune response (such as sIgA).
SIgA is the main effector of mucosal immunity, and plays an important role in mucosal immune defense. It has many biological functions, such as inhibiting pathogen adhesion, anti infection, immune clearance, anti allergy, promoting natural antibacterial factors, anti-tumor and maintaining immune homeostasis.
Bacillus subtilis is a kind of traditional probiotics, which also has a variety of immunological activities, such as maintaining the normal intestinal flora structure, maintaining the barrier function of intestinal epithelium, promoting the development of intestinal related lymphoid tissue, and improving the innate immunity of animals.
This product is fermented by Bacillus subtilis and anti diarrhea Chinese medicine extract. Oral administration of this product can effectively induce the increase of intestinal M cells and non-specific SIgA antibody. Oral immunization can induce the secretion of SIgA antibody and IgG antibody of PEDV, and enhance the level of SIgA antibody of PEDV. To increase the content of IgA in colostrum of sows.
Usage and dosage:
Anti plague companion I
Spray: This product 1kg, pre dissolved in 30L 20% alcohol solution, water volume to 400L, used for 10 thousand square meters of spray, also can be in the top of the pig (PigHead) and the material trough, spray the smaller the better droplets.
Drinking water or mixing material: 100g of this product, 1000kg of water or 500kg of mixing material, once a day, continuous use for 7 days, long-term use in high-risk areas.
Anti plague companion II
Mixed feed: This product 1kg can be mixed 500kg, used for 3-5 days, severe double. It can be used in combination with anti plague partner I to effectively prevent and control the current epidemic infectious diseases.